Understanding how brain cells help with memory in adults
Cell-type, circuit and network mechanisms of adult oligodendrogenesis in memory storage and retrieval
This study is looking at how certain brain cells help with memory by figuring out how they change when we learn new things, especially when it comes to remembering things that scare us, and it's for anyone interested in understanding more about how our brains work with memories.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11078183 on NIH RePORTER |
What this research studies
This research investigates the role of oligodendrocyte precursor cells in the adult brain and their contribution to memory storage and retrieval. By examining how these cells produce myelinating oligodendrocytes, the study aims to uncover the relationship between myelination and learning processes. The researchers will explore which specific cell types in the brain become myelinated after learning experiences and how this myelination affects memory-related neural circuits. This work could provide insights into the mechanisms of memory encoding and recall, particularly in the context of fear memories.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who may experience memory impairments or are interested in understanding memory processes.
Not a fit: Patients with severe cognitive impairments or neurological disorders that significantly affect brain function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing memory function in adults.
How similar studies have performed: Previous research has shown promising results in understanding myelination's role in learning and memory, indicating that this approach has potential for significant findings.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Kheirbek, Mazen a — University of California, San Francisco
- Study coordinator: Kheirbek, Mazen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.