Understanding how brain cells for balance develop and function
Functional maturation of interneurons that mediate the vestibulo-ocular reflex - Renewal - Resubmission - 1
This study is looking at special brain cells that help us keep our balance and see clearly, and it aims to understand how these cells grow and work, which could lead to better treatments for people who have trouble with balance or vision.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11047298 on NIH RePORTER |
What this research studies
This research investigates the development and function of specific brain cells called interneurons that are crucial for maintaining balance and stabilizing vision. By examining how these cells mature and respond to instability, the research aims to uncover the mechanisms behind vestibular reflexes, which are essential for coordinating eye movements and balance. The study employs advanced techniques to differentiate between various types of interneurons based on their developmental timeline, which could lead to insights into how these cells contribute to balance and motor learning. This knowledge may help in developing targeted therapies for individuals with vestibular dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research include children with vestibular dysfunction and older adults experiencing balance issues.
Not a fit: Patients with stable vestibular function or those not experiencing balance-related issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for balance disorders, potentially enhancing the quality of life for affected individuals.
How similar studies have performed: Previous research has shown success in understanding neural circuits in other areas of the brain, suggesting that this approach could yield valuable insights into vestibular function as well.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Schoppik, David — New York University School of Medicine
- Study coordinator: Schoppik, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.