Understanding how brain cells develop and organize during human brain growth
Official title: Elucidating the Signaling Landscapes Underlying Cellular and Regional Specification During Human Brain Development
Funded at Emory University · NIH-11021071 · Data updated 2026-11-12
This study is looking at how the signals in our bodies help shape the human brain as it grows, which could lead to better treatments for brain development issues in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | February 1, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $655,910 |
| NIH project number | 5R01MH133612-02 |
| Project ID | NIH-11021071 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with developmental brain disorders or conditions that affect brain structure and function.
✕Less likely to help
Patients with fully developed brains and no neurological or developmental disorders may not receive direct benefits from this research.
What this research studies
This research investigates the complex signaling pathways that guide the development of the human brain, focusing on how these pathways influence cell differentiation and tissue formation over time. By using advanced techniques to analyze these signaling processes, the study aims to uncover the mechanisms that allow for the precise organization of brain regions and cell types. Patients may benefit from insights gained into brain development, which could inform future treatments for developmental disorders. The research employs innovative models and molecular tools to explore these processes in a controlled environment.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating developmental brain disorders.
How similar studies have gone: Other research in developmental biology has shown success in understanding signaling pathways, but this specific approach is novel and aims to provide new insights into human brain development.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Birey, Fikri — Emory University
- Study coordinator: Birey, Fikri
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.