Understanding how brain cells develop and connect in autism and related disorders
DEFINING MECHANISMS OF PROGENITOR BALANCE AND NEURONAL CONNECTIVITY
This study is looking at how certain brain cells work together to form connections in the developing brain, which is important for understanding conditions like autism, and it uses special techniques to learn more about these processes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11083035 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that regulate the balance of progenitor cells and the connectivity of neurons in the developing cerebral cortex. By studying how radial progenitors and intermediate progenitors interact, the research aims to uncover the molecular processes that lead to the proper formation of neuronal circuits. This understanding is crucial for addressing neurodevelopmental disorders such as autism spectrum disorder, where these processes may be disrupted. The research employs advanced techniques in cell lineage tracing and signaling analysis to explore these fundamental biological questions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorder or related neurodevelopmental conditions.
Not a fit: Patients with neurodevelopmental disorders unrelated to progenitor cell balance or neuronal connectivity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and therapeutic strategies for treating autism and other neurodevelopmental disorders.
How similar studies have performed: Previous research has shown promising results in understanding neuronal development and connectivity, suggesting that this approach could yield valuable insights.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Anton, Eva S — Univ of North Carolina Chapel Hill
- Study coordinator: Anton, Eva S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.