Understanding how brain cells control movement and decision-making
Mapping neural ensemble computations to biological circuitry in motor control and decision making - Resubmission - 1
This study looks at how brain cells work together to help us move and make choices, using mice to learn more about these processes, which could eventually lead to better treatments for conditions like Parkinson's disease and help people recover from strokes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11089395 on NIH RePORTER |
What this research studies
This research investigates how groups of neurons in the brain work together to control movement and make decisions. By using advanced techniques in mice, the study aims to uncover the processes that transform high-level decisions into specific commands for body movements. The researchers employ mathematical tools to analyze neural activity, which could lead to better treatments for motor disorders like Parkinson's disease and recovery from strokes. The findings may provide insights into how the brain's biological circuitry functions under various conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from motor disorders such as Parkinson's disease or those recovering from strokes.
Not a fit: Patients with non-neurological conditions or those not experiencing motor control issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients with motor disorders and enhance recovery strategies for those affected by strokes.
How similar studies have performed: Previous research using similar approaches in monkeys has yielded significant insights into motor control, suggesting potential for success in this study.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Kaufman, Matthew Tyler — University of Chicago
- Study coordinator: Kaufman, Matthew Tyler
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.