Understanding how brain cells connect in the motor cortex of rodents and primates
Scalable integration of cell types and connectivity in the motor cortex of rodents and non-human primates
This study is exploring how different nerve cells in the part of the brain that controls movement work together, using special tools to create a detailed map of their connections, which will help us learn more about how the brain functions and how it can be affected by disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Allen Institute NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10369307 on NIH RePORTER |
What this research studies
This research investigates the intricate connections between different types of neurons in the motor cortex, which is crucial for movement control. By using advanced techniques like electron microscopy and transcriptomic profiling, the study aims to create a detailed map of neuronal connectivity. This approach will help researchers understand how individual neurons and their types interact, which is essential for understanding brain function and disorders. The research will involve both rodents and non-human primates to ensure a comprehensive understanding across species.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with motor control disorders or neurological conditions affecting movement.
Not a fit: Patients with conditions unrelated to motor control or those not affected by neurological disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding motor control and neurological disorders, potentially improving treatment options for patients.
How similar studies have performed: Other research has shown success in mapping neuronal connections using similar advanced techniques, indicating a promising approach for this study.
Where this research is happening
Seattle, United States
- Allen Institute — Seattle, United States (Active)
Researchers
- Principal investigator: Reid, R Clay — Allen Institute
- Study coordinator: Reid, R Clay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.