Understanding how brain bleeding affects lung health in older adults
Official title: Pathobiology of ICH in Aging
Funded at University of Texas Hlth Sci Ctr Houston · NIH-11074121 · Data updated 2026-11-12
This study is looking at how bleeding in the brain affects lung health in older adults, especially how aging changes the immune system's response after a stroke, with the goal of finding better treatments for seniors who experience this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | April 12, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $461,926 |
| NIH project number | 5R01NS133693-02 |
| Project ID | NIH-11074121 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who have experienced an intracerebral hemorrhage.
✕Less likely to help
Patients under the age of 65 or those who have not experienced an intracerebral hemorrhage may not benefit from this research.
What this research studies
This research investigates the relationship between intracerebral hemorrhage (ICH) and lung health in individuals aged 65 and older. It focuses on how aging influences immune responses that may worsen outcomes after a stroke, particularly through the role of specific immune cells in the lungs. By studying the effects of a protein called CCL11 on immune cells, the research aims to uncover mechanisms that could lead to better treatment strategies for older patients who suffer from ICH. The approach includes both laboratory studies and potential clinical implications for managing stroke in the elderly.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and outcomes for older patients who experience strokes.
How similar studies have gone: Previous research has indicated that understanding immune responses in stroke patients can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
-
University of Texas Hlth Sci Ctr Houston
Houston, United States Active
Researchers
- Principal investigator: Jung, Joo Eun — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Jung, Joo Eun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.