Understanding how brain and spinal cord connections control movement
Coordination of Structure and Function in Corticospinal and Corticostriatal Pathways
This study is looking at how the brain and spinal cord work together to help us move, and it aims to find new ways to improve treatments for movement disorders like Parkinson's disease and dystonia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11056052 on NIH RePORTER |
What this research studies
This research investigates how the brain and spinal cord work together to coordinate movement by examining the connections of corticospinal neurons, which are crucial for motor control. Using advanced technologies, the study aims to map and analyze the synaptic connections these neurons make in both the spinal cord and the striatum, which is involved in motor function. By uncovering the organization and function of these neural circuits, the research seeks to improve our understanding of movement disorders like Parkinson's disease and dystonia. Patients may benefit from insights that could lead to better treatment options for these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from movement disorders such as Parkinson's disease or dystonia.
Not a fit: Patients with movement disorders not related to brain dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for movement disorders caused by brain dysfunction.
How similar studies have performed: Other research has shown promise in understanding neural circuits related to movement, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- New York University — New York, United States (Active)
Researchers
- Principal investigator: Nelson, Anders — New York University
- Study coordinator: Nelson, Anders
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.