Understanding how brain activity relates to stroke outcomes
Official title: The relationship between neuronal activity and stroke
Funded at University of California-Irvine · NIH-10989916 · Data updated 2026-11-12
This study is looking at how brain activity after a stroke can be affected by sensory stimulation, like touch or sound, in the first few hours, and it aims to find out the best ways to help the brain heal after a stroke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | December 15, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $415,549 |
| NIH project number | 5R01NS126526-03 |
| Project ID | NIH-10989916 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals at risk for ischemic strokes or those who have experienced a stroke.
✕Less likely to help
Patients with non-ischemic strokes or those who do not have access to the required imaging and stimulation techniques may not benefit from this research.
What this research studies
This research investigates the connection between neuronal activity and the effects of stroke, particularly focusing on ischemic strokes caused by blood flow blockage. Using a rat model, the study examines how sensory stimulation in the early hours after a stroke can either protect or harm brain tissue, depending on the timing and location of the stimulation. Advanced imaging techniques and machine learning will be utilized to analyze the spread of neuronal activity in the brain, aiming to uncover critical insights into stroke recovery and prevention.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for protecting brain tissue during strokes, potentially improving recovery outcomes for patients.
How similar studies have gone: Previous research has shown promising results using sensory stimulation to influence stroke outcomes, suggesting that this approach may be effective.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Frostig, Ron D — University of California-Irvine
- Study coordinator: Frostig, Ron D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.