Understanding how brain activity relates to epilepsy and its treatment
Cellular and network mechanisms of epilepsy and neuromodulation
This study is looking at how epilepsy works in the brain and aims to find ways to predict seizures and improve treatment for people who don’t respond to medication, using electrical stimulation to help manage their condition better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11129235 on NIH RePORTER |
What this research studies
This research investigates the cellular and network mechanisms underlying epilepsy, a serious brain disorder affecting millions. It focuses on identifying specific biomarkers present between seizures that can help predict seizure risk and improve management. The study also explores the effects of neuromodulation through electrical stimulation as a treatment for patients with drug-resistant epilepsy. By combining expertise from various fields, the research aims to uncover the neural mechanisms involved and optimize stimulation parameters for better clinical outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with epilepsy, particularly those who experience drug-resistant seizures.
Not a fit: Patients with well-controlled epilepsy or those who do not experience seizures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prediction and management of seizures, enhancing treatment options for patients with epilepsy.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for epilepsy and the potential of neuromodulation, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Han, Xue — Boston University (Charles River Campus)
- Study coordinator: Han, Xue
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.