Understanding how brain activity changes during learning
Official title: CRCNS: Emergence of coordinated multi-region brain activity supporting behavior
Funded at University of California, San Diego · NIH-10917412 · Data updated 2026-11-12
This study is looking at how brain cells work together when we learn new things, which could help us understand memory better and lead to new treatments for conditions like Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $112,245 |
| NIH project number | 5R01NS135853-02 |
| Project ID | NIH-10917412 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing early symptoms of Alzheimer's disease or related dementias.
✕Less likely to help
Patients with advanced Alzheimer's disease or those with other unrelated neurological conditions may not benefit from this research.
What this research studies
This research investigates how interactions between neurons in the brain change to support learning and behavior. By using advanced optical techniques, researchers will map these interactions at a cellular level, allowing them to observe how the brain adapts during the learning of goal-directed tasks. The study aims to uncover the mechanisms behind learning and memory by analyzing both local and widespread brain activity. Patients may benefit from insights gained about brain function and potential new treatments for conditions like Alzheimer's disease.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promising results in understanding brain dynamics and learning mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Aljadeff, Johnatan — University of California, San Diego
- Study coordinator: Aljadeff, Johnatan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.