Understanding how brain activity changes during learning
CRCNS: Emergence of coordinated multi-region brain activity supporting behavior
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10917412
This study is looking at how brain cells work together when we learn new things, which could help us understand memory better and lead to new treatments for conditions like Alzheimer's disease.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10917412 on ClinicalTrials.gov |
What this research studies
This research investigates how interactions between neurons in the brain change to support learning and behavior. By using advanced optical techniques, researchers will map these interactions at a cellular level, allowing them to observe how the brain adapts during the learning of goal-directed tasks. The study aims to uncover the mechanisms behind learning and memory by analyzing both local and widespread brain activity. Patients may benefit from insights gained about brain function and potential new treatments for conditions like Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing early symptoms of Alzheimer's disease or related dementias.
Not a fit: Patients with advanced Alzheimer's disease or those with other unrelated neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for Alzheimer's disease and related dementias.
How similar studies have performed: Previous research has shown promising results in understanding brain dynamics and learning mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALJADEFF, JOHNATAN — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: ALJADEFF, JOHNATAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease