Understanding how brain activity changes during development

Development and Divergence of Whole-Brain Activity

NIH-funded research Northeastern University · NIH-11064835

This study looks at how the brain activity of tiny worms changes as they grow up, helping us understand how their brains work and how this affects their behavior.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNortheastern University NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11064835 on NIH RePORTER

What this research studies

This research investigates how the brain activity of the worm Caenorhabditis elegans changes as it develops from a newly-hatched larva to an adult. By using advanced calcium imaging techniques, the researchers will observe the brain's activity patterns and how they relate to the brain's structure and connectivity. The study aims to uncover the variability in brain function among individual worms and how this affects their behavior. This research could provide insights into the fundamental principles of brain function and development.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals interested in the biological and neurological sciences, particularly those studying developmental biology or neuroscience.

Not a fit: Patients with conditions unrelated to neurological development or those not engaged in scientific research may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of brain development and function, potentially informing treatments for neurological conditions.

How similar studies have performed: While this research focuses on a specific model organism, similar approaches in studying brain connectivity and function have shown promise in other contexts, suggesting potential for success.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.