Understanding how brain activity can help restore consciousness and behavior after injury or anesthesia
Official title: Mechanisms and Functions of Cortical Activity to Restore Behavior
Funded at Weill Medical Coll of Cornell Univ · NIH-10874730 · Data updated 2026-11-12
This study is looking at how certain brain pathways can help people who are waking up from brain injuries, anesthesia, or COVID-19-related conditions, with the goal of finding new ways to improve their alertness and movement.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $487,477 |
| NIH project number | 5R01NS129836-02 |
| Project ID | NIH-10874730 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced acquired brain injuries, those recovering from anesthesia, and COVID-19 survivors with altered consciousness.
✕Less likely to help
Patients with stable neurological conditions or those who do not exhibit altered consciousness are unlikely to benefit from this research.
What this research studies
This research investigates the neural mechanisms involved in restoring consciousness and behavior in patients recovering from brain injuries, anesthesia, or COVID-19 related altered states. The team will explore how stimulating specific brain pathways can promote wakefulness and improve motor functions. By monitoring brain activity during the transition to wakefulness, they aim to identify patterns that correlate with behavioral changes, potentially leading to new therapeutic approaches for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for restoring consciousness and motor function in patients recovering from severe brain injuries or anesthesia.
How similar studies have gone: Previous research has shown promising results in stimulating brain pathways to restore consciousness, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Calderon, Diany Paola — Weill Medical Coll of Cornell Univ
- Study coordinator: Calderon, Diany Paola
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.