Understanding how brain activity affects movement control
The role of cortical and subcortical β-bursts in the cognitive control of human movement
['FUNDING_R01'] · UNIVERSITY OF IOWA · NIH-10839483
This study is looking at how certain brain activity patterns help control movement, especially for people with movement disorders like Parkinson's Disease, to find new ways to improve their treatment and understanding of their condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF IOWA (nih funded) |
| Locations | 1 site (IOWA CITY, UNITED STATES) |
| Trial ID | NIH-10839483 on ClinicalTrials.gov |
What this research studies
This research investigates the role of specific brain activity patterns, known as β-bursts, in controlling human movement. By examining how these bursts occur in both the cortical and subcortical regions of the brain, the study aims to uncover their relationship with motor processes, particularly in individuals with movement disorders like Parkinson's Disease. The research employs advanced neurophysiological techniques to analyze these burst events, which may provide insights into the underlying mechanisms of motor control and potential new treatment approaches. Patients may benefit from a better understanding of their movement disorders and the development of targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with movement disorders, particularly those with Parkinson's Disease.
Not a fit: Patients with movement disorders not related to β-burst activity or those without neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for movement disorders, enhancing patients' quality of life.
How similar studies have performed: Previous research has shown promising results in understanding β-activity in animal models, but this approach in humans is relatively novel.
Where this research is happening
IOWA CITY, UNITED STATES
- UNIVERSITY OF IOWA — IOWA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WESSEL, JAN R — UNIVERSITY OF IOWA
- Study coordinator: WESSEL, JAN R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.