Understanding how brain activity affects decision-making in mice
Histology Core
This study looks at how brain activity affects the choices mice make, especially when they're focused on a task, and it aims to create a helpful way to analyze brain data so that researchers can better understand how the brain works and share their findings easily.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia Univ New York Morningside NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10906282 on NIH RePORTER |
What this research studies
This research investigates the relationship between brain activity and behavior in mice, particularly focusing on how internal states like task engagement influence decision-making. By using advanced imaging techniques, the study aims to create a standardized framework for analyzing brain data across different experiments. The methodology involves registering electrophysiological recordings into a common anatomical atlas, which will help synthesize findings into a comprehensive model of brain function. This work will also develop open-source software to facilitate data analysis and improve the reproducibility of results.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals with conditions affecting decision-making or cognitive function.
Not a fit: Patients with conditions unrelated to brain function or decision-making may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain function and decision-making processes, potentially leading to new treatments for neurological disorders.
How similar studies have performed: Previous research using similar imaging and analysis techniques has shown promise in understanding brain function, indicating that this approach is both relevant and potentially impactful.
Where this research is happening
New York, United States
- Columbia Univ New York Morningside — New York, United States (Active)
Researchers
- Principal investigator: Mrsic-Flogel, Thomas — Columbia Univ New York Morningside
- Study coordinator: Mrsic-Flogel, Thomas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.