Understanding how brain activity affects chronic pain
Explosive Synchronization of Brain Network Activity in Chronic Pain
This study is looking at how brain activity affects chronic pain, especially for people with fibromyalgia, and it aims to use gentle brain stimulation to help reduce pain sensitivity and improve comfort.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10653975 on NIH RePORTER |
What this research studies
This research investigates the role of brain network activity in chronic pain conditions, particularly fibromyalgia. It explores how an imbalance in brain activity may lead to heightened sensitivity to pain and aims to use non-invasive brain stimulation techniques to address this issue. By applying targeted stimulation, the researchers hope to reduce the hypersensitivity of brain networks and alleviate pain symptoms. Patients may be monitored using techniques like electroencephalography (EEG) to assess changes in brain activity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic pain conditions, particularly those diagnosed with fibromyalgia.
Not a fit: Patients with acute pain conditions or those not experiencing chronic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, effective treatments for chronic pain conditions, improving the quality of life for many patients.
How similar studies have performed: While the concept of explosive synchronization in brain networks is relatively novel, similar approaches using non-invasive brain stimulation have shown promise in other areas of pain management.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Dasilva, Alexandre — University of Michigan at Ann Arbor
- Study coordinator: Dasilva, Alexandre
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.