Understanding how bone morphogenetic proteins influence cell development in vertebrates
Official title: Interpreting Bone Morphogenetic Protein Gradients in Vertebrate Development
Funded at State University New York Stony Brook · NIH-10929342 · Data updated 2026-11-12
This study is looking at how certain proteins help shape the development of fish embryos, which can teach us about human development, by changing the amount of these proteins and seeing how it affects the cells' movements and roles.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project start | September 23, 2023 |
| Project end | September 22, 2025 |
| Funding year | 2024 |
| Award (this year) | $41,277 |
| NIH project number | 5F31GM150206-02 |
| Project ID | NIH-10929342 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in developmental disorders or diseases related to cell signaling and fate decisions.
✕Less likely to help
Patients with conditions unrelated to developmental biology or those not affected by cell signaling pathways may not benefit from this research.
What this research studies
This research investigates how bone morphogenetic proteins (BMPs) guide the development of vertebrates by influencing cell behavior and fate decisions. Using zebrafish embryos, which are transparent and share many genes with humans, the study will manipulate BMP concentrations and observe how these changes affect cell migration and identity. The research aims to uncover the mechanisms by which progenitor cells interpret BMP signals, which is crucial for understanding developmental processes and potential disease mechanisms.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of developmental biology and lead to advancements in regenerative medicine and cancer treatment.
How similar studies have gone: Previous research has shown success in using zebrafish as models for studying developmental processes, indicating that this approach is promising.
Where this research is happening
-
State University New York Stony Brook
Stony Brook, United States Active
Researchers
- Principal investigator: Tello, Courtney — State University New York Stony Brook
- Study coordinator: Tello, Courtney
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.