Understanding how body tissues communicate to manage sugar and fat
Chemical interrogation of metabolic tissue crosstalk
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-11141858
This project aims to uncover new ways our body's tissues talk to each other to control blood sugar and fat, which could help people with adult-onset diabetes.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11141858 on ClinicalTrials.gov |
What this research studies
Our body's different tissues, like fat and muscle, constantly communicate to keep our blood sugar and fat levels balanced. This communication happens through special proteins released into the blood. Many of these communication proteins are still unknown, and finding them could lead to new ways to treat conditions like diabetes. Researchers are developing a new chemical method to directly measure these proteins as they are released from tissues in living animals. This approach helps us understand how these proteins work in a real-life setting, offering insights that older lab methods couldn't provide.
Who could benefit from this research
Good fit: This foundational work is not directly recruiting patients but focuses on understanding the underlying biology relevant to individuals with adult-onset diabetes and metabolic conditions.
Not a fit: Patients seeking immediate treatment options would not directly benefit from this early-stage discovery research.
Why it matters
Potential benefit: If successful, this work could identify new biological pathways and targets for developing innovative treatments for adult-onset diabetes, obesity, and related metabolic disorders.
How similar studies have performed: This project builds upon a recently developed chemical methodology that has shown success in directly measuring secreted proteins in living animals, offering a novel approach compared to traditional methods.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LONG, JONATHAN Z — STANFORD UNIVERSITY
- Study coordinator: LONG, JONATHAN Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus