NIH-funded research Fellowship grant

Understanding how body awareness affects psychosis symptoms

Official title: Computational Modeling of Interoceptive Perception across the Psychosis-Spectrum

Funded at Trustees of Indiana University · NIH-10901270 · Data updated 2026-11-12

This study is looking at how feeling things like your heartbeat and body temperature might affect experiences of psychosis, like seeing or hearing things that aren't there, and it's designed for people who have these experiences to help find better treatments.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionTrustees of Indiana University
NIH-funded
Lab location1 site (Bloomington, United States)
Project startAugust 1, 2024
Project endJuly 31, 2026
Funding year2024
Award (this year)$48,974
NIH project number1F31MH136742-01
Project IDNIH-10901270 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals experiencing psychosis symptoms, whether diagnosed or subclinical.

Less likely to help

Patients with no psychosis symptoms or those who do not experience cognitive disturbances may not benefit from this research.

What this research studies

This research investigates how the perception of internal body states, such as heartbeat and temperature, influences experiences of psychosis, including hallucinations and delusions. By using non-invasive methods to manipulate these internal states, the study aims to understand their relationship with cognitive functions and psychotic symptoms. The approach involves computational modeling to analyze how these internal perceptions can be disrupted in individuals experiencing psychosis. This could lead to new insights into the mechanisms of psychosis and inform the development of targeted treatments.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals experiencing psychosis symptoms.

How similar studies have gone: While the approach of manipulating internal body states in relation to psychosis is relatively novel, similar studies in related fields have shown promising results.

Where this research is happening

  • Trustees of Indiana University
    Bloomington, United States
    Active

Researchers

  • Principal investigator: Herms, Emma — Trustees of Indiana University
  • Study coordinator: Herms, Emma

Related research

Other NIH-funded projects on the same topics.

  • Psychosis in diverse settings across the world

    This project studies how psychotic disorders show up and respond to treatment in adults with diverse backgrounds, including populations in Africa, the Caribbean, and other Global South settings.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592428

  • Psychosis in Diverse Settings: Understanding Symptoms and Treatment Across Global South

    A human-facing study will look at how psychotic disorders present and respond to treatment in adults from Africa, the Caribbean, and other Global South settings, using genetic and clinical data.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592427

  • A new online brain-scan-style tool to spot early psychosis risk

    A new online-based set of tasks and a computer model aims to identify people at high risk for developing psychosis earlier and more accurately.

    NIH research Northwestern University · Chicago, United States · NIH-11590585

  • Genetic clues for early-onset psychosis in Latino youth

    This project looks at the genes of young people with early-onset psychosis and compares them with similar youths without psychosis to find genetic factors that contribute to the illness.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11554752

  • Biomarkers to tailor rehab for Veterans with schizophrenia

    A clinician-scientist is developing a brain-based biomarker to guide personalized rehabilitation for Veterans with schizophrenia.

    NIH research VA San Diego Healthcare System · San Diego, United States · NIH-11552825

  • Computational analysis of facial expression in early psychosis

    Aims to develop computer-based measures of facial expression in people at risk for or with schizophrenia to help track symptoms and guide future trials.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11539126

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.