Understanding how BMP signaling affects cell types in the intestine
Official title: Mechanisms of BMP signaling driving tissue pattern in the intestine
Funded at Rutgers, the State Univ of N.j. · NIH-10997585 · Data updated 2026-11-12
This study is looking at how a special protein in the gut helps balance the growth of stem cells and nutrient-absorbing cells, which could help us understand and improve treatments for certain gut diseases.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | July 4, 2024 |
| Project end | July 3, 2026 |
| Funding year | 2024 |
| Award (this year) | $41,882 |
| NIH project number | 1F31DK137596-01A1 |
| Project ID | NIH-10997585 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with gastrointestinal disorders or those at risk for conditions related to improper cell differentiation in the intestine.
✕Less likely to help
Patients with gastrointestinal diseases unrelated to BMP signaling or those who do not have issues with cell differentiation may not benefit from this research.
What this research studies
This research investigates the role of Bone Morphogenetic Protein (BMP) signaling in the intestine, focusing on how it influences the balance between stem cells and specialized cells that absorb nutrients. By examining the molecular mechanisms behind this signaling pathway, the study aims to uncover why certain gastrointestinal diseases occur. The research utilizes advanced techniques to analyze how BMP signaling affects cell differentiation and proliferation, which could lead to better understanding and treatment of related conditions.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for gastrointestinal diseases by targeting the mechanisms that regulate cell differentiation and proliferation.
How similar studies have gone: Other research has shown promising results in understanding BMP signaling in various tissues, suggesting that this approach could yield valuable insights in the gastrointestinal context as well.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Logerfo, Alexandra — Rutgers, the State Univ of N.j.
- Study coordinator: Logerfo, Alexandra
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.