Understanding how blood vessels interact with hair follicle stem cells in mouse skin
Official title: Investigating the coordinated endothelial-epithelial interactions in adult hair cycle of mouse skin
Funded at Cornell University · NIH-11064831 · Data updated 2026-11-12
This study is looking at how blood vessels and hair follicle stem cells work together in mouse skin to help with hair growth and healing, which could lead to new ways to treat skin problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project start | April 28, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $451,666 |
| NIH project number | 5R01AR081021-03 |
| Project ID | NIH-11064831 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be adults interested in skin health and hair regeneration.
✕Less likely to help
Patients with conditions unrelated to skin regeneration or hair follicle activity may not receive any benefit from this research.
What this research studies
This research investigates the interactions between blood vessels and hair follicle stem cells in mouse skin, focusing on how these interactions influence hair growth and regeneration. By using genetic targeting techniques, the study aims to identify specific signaling molecules in endothelial cells that regulate the activity of hair follicle stem cells. The findings could provide insights into the mechanisms of skin regeneration and the role of blood vessels in this process, potentially leading to advancements in treating skin-related conditions.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing skin regeneration and treating hair loss disorders.
How similar studies have gone: While the specific approach of targeting endothelial cell signaling in hair follicle stem cells is novel, similar studies have shown promise in understanding tissue regeneration.
Where this research is happening
-
Cornell University
Ithaca, United States Active
Researchers
- Principal investigator: Tumbar, Tudorita — Cornell University
- Study coordinator: Tumbar, Tudorita
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.