Understanding how blood vessels in the placenta develop and function
Endothelial regulation of the blood-placental barrier
['FUNDING_CAREER'] · UNIVERSITY OF PENNSYLVANIA · NIH-10947771
This study is looking at how blood vessels in the placenta grow and work, which is really important for making sure the baby gets the nutrients and oxygen it needs, and it could help improve pregnancy outcomes for moms and babies facing challenges.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10947771 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that regulate the growth and function of blood vessels in the placenta, which are essential for nutrient and oxygen exchange between the mother and fetus. By using advanced genetic tools and imaging techniques, the study aims to uncover the cellular and molecular processes that affect placental vascular development. The research also explores how the placental blood vessels impact fetal growth and maternal cardiovascular health, potentially leading to better outcomes for pregnancies at risk of complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals, particularly those experiencing complications related to fetal growth or cardiovascular health.
Not a fit: Patients who are not pregnant or those with unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of conditions like fetal growth restriction and maternal cardiovascular issues during pregnancy.
How similar studies have performed: Other research has shown promise in understanding vascular development in various contexts, but this specific focus on the placental blood vessels is relatively novel.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GAO, SIQI — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: GAO, SIQI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.