Understanding how blood vessels grow and respond to signals in the body
MOLECULAR AND CELLULAR CONTROL OF ANGIOGENESIS
This study looks at how the cells that line our blood vessels react to different signals when new blood vessels are formed, which could help us understand and improve treatments for conditions related to blood vessel health, especially during healing and heart-related issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10744775 on NIH RePORTER |
What this research studies
This research investigates how endothelial cells, which line blood vessels, respond differently to various signals during the formation of new blood vessels. By studying the molecular pathways involved, such as VEGF-A and BMP, the research aims to uncover the reasons behind the diverse behaviors of these cells. The team will explore how these responses change during processes like wound healing and how they relate to cardiovascular diseases. Patients may benefit from insights gained into blood vessel formation and function, which could lead to improved treatments for vascular disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cardiovascular disorders or those interested in the mechanisms of blood vessel formation.
Not a fit: Patients with non-cardiovascular related conditions or those not affected by vascular issues may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for cardiovascular diseases by enhancing our understanding of blood vessel growth and repair.
How similar studies have performed: Previous research has shown promising results in understanding endothelial cell behavior and its implications for vascular health, indicating that this approach is built on established findings.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Bautch, Victoria L — Univ of North Carolina Chapel Hill
- Study coordinator: Bautch, Victoria L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.