Understanding how blood vessel problems contribute to vascular dementia
Novel regulation of vascular dementia
['FUNDING_R01'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11169865
This study is looking at how problems with blood vessels might lead to vascular dementia, a common cause of memory and thinking issues, and it aims to find new ways to help people with this condition by understanding the role of genetics and certain proteins in blood vessel health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-11169865 on ClinicalTrials.gov |
What this research studies
This research investigates the connection between vascular dysfunction and vascular dementia (VaD), which is a leading cause of cognitive decline similar to Alzheimer's disease. The study aims to uncover new mechanisms that link issues in blood vessels to cognitive impairments, focusing on genetic risk factors and the role of specific proteins in vascular health. By exploring the relationship between various vascular diseases and dementia, the research seeks to provide insights that could lead to improved treatment strategies for patients suffering from these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with vascular dementia or those at risk due to vascular diseases such as atherosclerosis or stroke.
Not a fit: Patients with dementia not related to vascular issues or those with other unrelated cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that better address the underlying causes of vascular dementia and improve cognitive health in affected patients.
How similar studies have performed: Previous research has shown promising results in understanding the links between vascular health and cognitive decline, suggesting that this approach could yield valuable insights.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHEN, YABING — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: CHEN, YABING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.