Understanding how blood vessel problems contribute to dementia and cognitive decline

BCCMA: Interplay of Novel Mediators of Vascular Aging Pathologies

['FUNDING_OTHER'] · PORTLAND VA MEDICAL CENTER · NIH-11075808

This study is looking at how problems with blood vessels might affect thinking and memory in people with vascular dementia and Alzheimer's, hoping to find new ways to help improve brain health and treatment options.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPORTLAND VA MEDICAL CENTER (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-11075808 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between vascular health and cognitive decline, particularly focusing on vascular dementia and Alzheimer's disease. It aims to uncover the mechanisms by which vascular dysfunctions in the cardiovascular and cerebrovascular systems affect cognitive functions. By studying genetic risk factors and the role of specific proteins, the research seeks to identify new pathways that could lead to better treatment strategies for dementia. Patients may benefit from insights gained into how vascular health impacts brain function.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing cognitive decline or diagnosed with vascular dementia or Alzheimer's disease.

Not a fit: Patients with cognitive impairments not related to vascular issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients suffering from vascular dementia and Alzheimer's disease.

How similar studies have performed: Previous research has shown promising results in understanding the links between vascular health and cognitive decline, suggesting that this approach could yield valuable insights.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.