Understanding how blood vessel growth supports bone healing
Osteo-Angio Coupling During Bone Repair - Resubmission - 1
This study is looking at how new blood vessels help bones heal after a fracture and how certain cells talk to each other during this process, which could lead to better treatments for bone injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10672338 on NIH RePORTER |
What this research studies
This research investigates the relationship between blood vessel growth and bone repair, focusing on how certain cells communicate during the healing process. It aims to understand the role of a specific signaling molecule, CXCL12, in promoting the formation of new blood vessels and its interaction with bone-forming cells. Using advanced imaging techniques and genetic models, the study will explore how these processes work together to enhance healing after fractures. Patients may benefit from insights that could lead to improved treatments for bone injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with fractures or conditions that impair bone healing.
Not a fit: Patients with stable bone conditions that do not require healing or those without fractures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance bone healing and recovery after fractures.
How similar studies have performed: Previous research has shown promising results in understanding the role of blood vessels in bone healing, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Leucht, Philipp — New York University School of Medicine
- Study coordinator: Leucht, Philipp
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.