Understanding how blood vessel growth helps the brain recover after a stroke in newborns
Endothelial tip cell-mediated angiogenesis and repair after neonatal stroke
This study looks at how newborns' brains heal after a stroke by understanding how blood vessels grow and repair damage, with the goal of finding better treatments to help these little ones recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10895576 on NIH RePORTER |
What this research studies
This research investigates the mechanisms of recovery in the brain following a stroke in newborns, focusing on how blood vessels grow and repair the damaged areas. It explores the role of specific cells and signaling pathways that are crucial for healing after a stroke. By studying these processes, the research aims to identify potential treatments that could enhance recovery and improve outcomes for affected infants. The approach includes examining the interactions between different cell types and the effects of growth factors in the developing brain.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns aged 0-4 weeks who have experienced a stroke or are at risk of brain injury.
Not a fit: Patients who are older than 4 weeks or who have not experienced a stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve recovery and reduce disability in infants who suffer from strokes.
How similar studies have performed: Previous research has shown promise in understanding angiogenesis and recovery mechanisms in other contexts, but this specific approach in neonatal stroke is relatively novel.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Gonzalez, Fernando Francisco — University of California, San Francisco
- Study coordinator: Gonzalez, Fernando Francisco
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.