Understanding how blood vessel formation helps bone healing
Examining endothelial cell and its plasticity in intramembranous bone regeneration
['FUNDING_R03'] · RUSH UNIVERSITY MEDICAL CENTER · NIH-10870794
This study is looking at how blood vessels and certain cells help bones heal after injuries or surgeries, with the goal of finding better treatments for people needing orthopedic or dental care.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RUSH UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10870794 on ClinicalTrials.gov |
What this research studies
This research investigates the processes involved in intramembranous bone regeneration, focusing on how blood vessel formation and endothelial cell behavior contribute to successful bone healing. By examining the transition of endothelial cells during this process, the study aims to uncover new therapeutic strategies that could improve outcomes for patients undergoing orthopedic or dental procedures. The research employs advanced techniques to analyze blood vessel formation and the role of specific cell types in bone regeneration.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals undergoing orthopedic or dental procedures that require bone regeneration.
Not a fit: Patients who do not require bone regeneration or are not undergoing related surgical procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved healing and success rates for orthopedic and dental implants.
How similar studies have performed: Previous research has shown promising results in understanding blood vessel formation in bone healing, suggesting that this approach could yield significant advancements.
Where this research is happening
CHICAGO, UNITED STATES
- RUSH UNIVERSITY MEDICAL CENTER — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KO, FRANK — RUSH UNIVERSITY MEDICAL CENTER
- Study coordinator: KO, FRANK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.