Understanding how blood vessel formation helps bone healing
Official title: Examining endothelial cell and its plasticity in intramembranous bone regeneration
Funded at Rush University Medical Center · NIH-10870794 · Data updated 2026-11-12
This study is looking at how blood vessels and certain cells help bones heal after injuries or surgeries, with the goal of finding better treatments for people needing orthopedic or dental care.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $158,000 |
| NIH project number | 1R03AR082927-01A1 |
| Project ID | NIH-10870794 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals undergoing orthopedic or dental procedures that require bone regeneration.
✕Less likely to help
Patients who do not require bone regeneration or are not undergoing related surgical procedures may not benefit from this research.
What this research studies
This research investigates the processes involved in intramembranous bone regeneration, focusing on how blood vessel formation and endothelial cell behavior contribute to successful bone healing. By examining the transition of endothelial cells during this process, the study aims to uncover new therapeutic strategies that could improve outcomes for patients undergoing orthopedic or dental procedures. The research employs advanced techniques to analyze blood vessel formation and the role of specific cell types in bone regeneration.
Why it matters
Potential benefit: If successful, this research could lead to improved healing and success rates for orthopedic and dental implants.
How similar studies have gone: Previous research has shown promising results in understanding blood vessel formation in bone healing, suggesting that this approach could yield significant advancements.
Where this research is happening
-
Rush University Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Ko, Frank — Rush University Medical Center
- Study coordinator: Ko, Frank
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.