Understanding how blood flow in the brain is controlled by nerve activity.
Local Neuronal Drive and Neuromodulatory Control of Activity in the Pial Neurovascular Circuit
This study is looking at how the brain controls blood flow and oxygen delivery, using special imaging tools and math, to help us understand how these processes work in both animals and people, which could lead to better treatments for brain-related conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11095742 on NIH RePORTER |
What this research studies
This research investigates the pial neurovascular circuit, which regulates blood flow in the brain through rhythmic oscillations. By using advanced imaging techniques and mathematical modeling, the study aims to connect brain activity patterns with blood flow dynamics. Patients may benefit from insights gained through this research, as it combines experimental methods with theoretical modeling to explore how oxygen transport is modulated in the brain. The research involves both animal models and human participants to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with neurological conditions that affect blood flow in the brain.
Not a fit: Patients with stable neurological conditions that do not impact blood flow may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of conditions related to brain blood flow and oxygen delivery.
How similar studies have performed: Previous research has shown promising results in understanding neurovascular dynamics, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Devor, Anna — Boston University (Charles River Campus)
- Study coordinator: Devor, Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.