Understanding how blood clotting works
Official title: Mechanisms in Blood Clotting
Funded at University of Michigan at Ann Arbor · NIH-11002685 · Data updated 2026-11-12
This study is looking at how blood clots form in our bodies, trying to understand the difference between normal healing and dangerous clots that can cause strokes or heart attacks, with the goal of finding new ways to help people with bleeding or clotting problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2031 |
| Funding year | 2025 |
| Award (this year) | $889,325 |
| NIH project number | 5R35HL171334-02 |
| Project ID | NIH-11002685 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with bleeding disorders or those at risk for thrombotic diseases such as strokes or heart attacks.
✕Less likely to help
Patients who do not have any blood clotting disorders or related conditions may not benefit from this research.
What this research studies
This research investigates the mechanisms that regulate blood clotting, focusing on how certain factors contribute to both normal clotting and harmful blood clots. The study aims to differentiate between hemostasis, which is the body's natural response to injury, and thrombosis, which can lead to serious conditions like strokes and heart attacks. By identifying specific molecules that trigger these processes, researchers hope to find new therapeutic targets that could improve treatment for clotting disorders. Patients may benefit from insights that could lead to better management of bleeding disorders and thrombotic diseases.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent harmful blood clots while preserving normal clotting functions.
How similar studies have gone: Previous research has shown promise in understanding blood clotting mechanisms, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Morrissey, James H. — University of Michigan at Ann Arbor
- Study coordinator: Morrissey, James H.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.