Understanding how blood clots form in puncture wounds
Resubmission: Structure/Function Determinants of Puncture Wound Thrombus Formation
['FUNDING_R01'] · UNIV OF ARKANSAS FOR MED SCIS · NIH-10838594
This study is looking at how blood clots form in puncture wounds from accidents or medical procedures, especially when common blood-thinning medications might lead to too much bleeding, to help improve treatments for people with these types of injuries.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF ARKANSAS FOR MED SCIS (nih funded) |
| Locations | 1 site (LITTLE ROCK, UNITED STATES) |
| Trial ID | NIH-10838594 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms of thrombus formation specifically in puncture wounds, which can occur due to accidents or medical procedures. The study aims to understand how platelets respond to these injuries, particularly in situations where traditional antiplatelet drugs may cause excessive bleeding. By utilizing advanced imaging techniques, the researchers will analyze the structure and function of blood clots at a microscopic level, providing insights that could improve treatment strategies for traumatic injuries. The goal is to fill existing knowledge gaps regarding how blood clots form in open wounds, which is crucial for managing bleeding complications.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced puncture wounds, whether from accidents or surgical procedures.
Not a fit: Patients with conditions unrelated to puncture wounds or those who do not experience bleeding complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of bleeding in patients with puncture wounds, enhancing recovery and reducing complications.
How similar studies have performed: Previous research has shown promise in understanding thrombus formation, but this specific focus on puncture wounds represents a novel approach.
Where this research is happening
LITTLE ROCK, UNITED STATES
- UNIV OF ARKANSAS FOR MED SCIS — LITTLE ROCK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STORRIE, BRIAN — UNIV OF ARKANSAS FOR MED SCIS
- Study coordinator: STORRIE, BRIAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.