NIH-funded research R01 grant

Understanding how blindness affects brain changes

Official title: Variability of Brain Reorganization in Blindness

Funded at Georgetown University · NIH-11019786 · Data updated 2026-11-12

This study looks at how the brains of people who became blind early in life adapt and change, with the hope of finding better ways to help them regain sight or use helpful tools.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgetown University
NIH-funded
Lab location1 site (Washington, United States)
Project startApril 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$476,286
NIH project number5R01EY034515-03
Project IDNIH-11019786 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 21 and older who have experienced early-onset blindness.

Less likely to help

Patients who are not blind or who have not experienced significant vision loss may not benefit from this research.

What this research studies

This research investigates how the brain reorganizes itself in individuals who are blind, particularly focusing on those who lost their sight early in life. By using advanced neuroimaging techniques and behavioral assessments, the study aims to map the brain's plasticity and understand how these changes impact the ability to restore sight or use assistive devices. The goal is to identify individual differences in brain reorganization that could inform personalized rehabilitation strategies for blind individuals.

Why it matters

Potential benefit: If successful, this research could lead to improved rehabilitation techniques for individuals with blindness, enhancing their ability to regain functional sight or effectively use sensory aids.

How similar studies have gone: Previous research has shown promising results in understanding brain plasticity in blind individuals, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Georgetown University
    Washington, United States
    Active

Researchers

  • Principal investigator: Striem-Amit, Ella Ruth — Georgetown University
  • Study coordinator: Striem-Amit, Ella Ruth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.