Understanding how bladder cancer evolves over time
Disease Progression Modeling of Bladder Cancer
['FUNDING_R01'] · MAYO CLINIC JACKSONVILLE · NIH-10674950
This study is looking at how bladder cancer changes over time by examining genetic differences in tissue samples, with the goal of finding better ways to diagnose and treat the disease for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC JACKSONVILLE (nih funded) |
| Locations | 1 site (JACKSONVILLE, UNITED STATES) |
| Trial ID | NIH-10674950 on ClinicalTrials.gov |
What this research studies
This research investigates the progression of bladder cancer by analyzing genetic changes that occur as the disease develops. Using a computational method, researchers will create models based on tissue samples to visualize how bladder cancer evolves, even when direct time-series data from patients is not available. By examining a large number of samples, the study aims to uncover patterns in tumor development that could lead to better diagnostics and treatments for patients. The approach builds on previous successes in breast cancer research, adapting it to bladder cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with bladder cancer who are undergoing treatment or have provided tissue samples.
Not a fit: Patients with non-malignant bladder conditions or those who have not been diagnosed with bladder cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for bladder cancer patients.
How similar studies have performed: Similar computational approaches have shown success in modeling breast cancer progression, indicating potential for success in bladder cancer as well.
Where this research is happening
JACKSONVILLE, UNITED STATES
- MAYO CLINIC JACKSONVILLE — JACKSONVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOODISON, STEVE — MAYO CLINIC JACKSONVILLE
- Study coordinator: GOODISON, STEVE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bladder Cancer, Urinary Bladder Cancer, Breast Cancer