Understanding How Bladder Cancer Changes Over Time
Disease Progression Modeling of Bladder Cancer
['FUNDING_R01'] · MAYO CLINIC JACKSONVILLE · NIH-10908472
This project uses advanced computer methods to understand how bladder cancer develops and changes, aiming to improve how we find and treat it.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC JACKSONVILLE (nih funded) |
| Locations | 1 site (JACKSONVILLE, UNITED STATES) |
| Trial ID | NIH-10908472 on ClinicalTrials.gov |
What this research studies
Cancer develops through many steps, with genetic changes accumulating over time. Since it's difficult to collect many tissue samples from a single person over the course of their disease, researchers are using a special computer method called CancerMapp. This method takes many 'snapshot' samples from different people to create a comprehensive picture of how the disease progresses. This approach has already helped understand breast cancer, and now the team is applying it to bladder cancer to uncover its evolutionary paths.
Who could benefit from this research
Good fit: This research primarily uses existing tissue samples and data, so direct patient participation in new sample collection is not the immediate focus.
Not a fit: Patients seeking immediate new treatments or direct clinical intervention would not directly benefit from this foundational modeling work.
Why it matters
Potential benefit: If successful, this work could lead to better ways to diagnose bladder cancer earlier, predict its course more accurately, and develop new, more effective treatments.
How similar studies have performed: The computational approach has shown utility in modeling breast cancer progression, identifying major trajectories to malignancy.
Where this research is happening
JACKSONVILLE, UNITED STATES
- MAYO CLINIC JACKSONVILLE — JACKSONVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GOODISON, STEVE — MAYO CLINIC JACKSONVILLE
- Study coordinator: GOODISON, STEVE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bladder Cancer, Breast Cancer, Breast Cancer Model, Cancer Diagnostics