Understanding how biopolymers and chromatin interact in 3D space
Models and Algorithms for Biological Networks and Polymers: Stochastic Probability Landscape and Chromatin Ensembles
This study is looking at how natural substances in our cells interact with DNA to better understand important processes like how embryos develop and how stem cells change, which could help improve future treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-11004079 on NIH RePORTER |
What this research studies
This research investigates the interactions of biopolymers and chromatin at both molecular and cellular levels. It employs advanced computational tools to create detailed models of molecular reaction networks and 3D chromatin structures. By analyzing these interactions, the research aims to uncover the mechanisms behind important biological processes such as embryonic development and stem cell differentiation. Patients may benefit from insights gained into cellular behaviors that could inform future therapies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals with conditions influenced by cellular processes, such as genetic disorders or developmental issues.
Not a fit: Patients with conditions unrelated to cellular behavior or genetic factors may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases related to cellular dysfunction and genetic disorders.
How similar studies have performed: Other research has shown promise in using computational models to understand biological networks, indicating that this approach could yield valuable insights.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Liang, Jie — University of Illinois at Chicago
- Study coordinator: Liang, Jie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.