Understanding how biomechanical signals affect fat tissue function and energy regulation
Official title: Role of Biomechanical Interfaces Created by Focal Adhesion Kinase in Catecholamine Signaling
Funded at University of California Berkeley · NIH-10998792 · Data updated 2026-11-12
This study is looking at how physical signals in the body affect brown fat and its role in burning energy, which could help us find new ways to manage weight and improve overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project start | September 10, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $681,144 |
| NIH project number | 1R01DK141135-01 |
| Project ID | NIH-10998792 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults over 21 years old who are interested in metabolic health and energy regulation.
✕Less likely to help
Patients with conditions unrelated to metabolic health or those under 21 years old may not benefit from this research.
What this research studies
This research investigates the role of biomechanical signals in the function of brown adipose tissue (BAT) and its impact on energy regulation in the body. The team aims to explore how these signals interact with catecholamine signaling, which is crucial for thermogenesis and energy expenditure. By examining the mechanisms involved, including the activation of specific proteins and cellular processes, the research seeks to uncover new insights into how fat tissue can be influenced by mechanical forces. This could lead to novel approaches for managing energy balance and metabolic health.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving metabolic health and managing conditions related to obesity and energy regulation.
How similar studies have gone: Previous research has shown promising results in understanding the role of biomechanical signals in metabolic processes, suggesting that this approach could yield significant insights.
Where this research is happening
-
University of California Berkeley
Berkeley, United States Active
Researchers
- Principal investigator: Stahl, Andreas — University of California Berkeley
- Study coordinator: Stahl, Andreas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.