Understanding how biomechanical signals affect fat tissue function and energy regulation

Role of Biomechanical Interfaces Created by Focal Adhesion Kinase in Catecholamine Signaling

NIH-funded research University of California Berkeley · NIH-10998792

This study is looking at how physical signals in the body affect brown fat and its role in burning energy, which could help us find new ways to manage weight and improve overall health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Berkeley NIH-funded
Lab location1 site (Berkeley, United States)
Project IDNIH-10998792 on NIH RePORTER

What this research studies

This research investigates the role of biomechanical signals in the function of brown adipose tissue (BAT) and its impact on energy regulation in the body. The team aims to explore how these signals interact with catecholamine signaling, which is crucial for thermogenesis and energy expenditure. By examining the mechanisms involved, including the activation of specific proteins and cellular processes, the research seeks to uncover new insights into how fat tissue can be influenced by mechanical forces. This could lead to novel approaches for managing energy balance and metabolic health.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who are interested in metabolic health and energy regulation.

Not a fit: Patients with conditions unrelated to metabolic health or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for improving metabolic health and managing conditions related to obesity and energy regulation.

How similar studies have performed: Previous research has shown promising results in understanding the role of biomechanical signals in metabolic processes, suggesting that this approach could yield significant insights.

Where this research is happening

Berkeley, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.