Understanding how biological, psychological, and social factors affect shoulder pain after surgery
Official title: Biopsychosocial Influence on Shoulder Pain
Funded at Duke University · NIH-10906219 · Data updated 2026-11-12
This study is looking at how various factors in your body, mind, and life can affect long-term pain after shoulder surgery, so we can find better ways to manage pain for each person based on their unique situation.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $618,722 |
| NIH project number | 5R01AR081796-02 |
| Project ID | NIH-10906219 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are scheduled for total shoulder arthroplasty.
✕Less likely to help
Patients who are not undergoing shoulder surgery or are under 21 years old may not benefit from this research.
What this research studies
This research investigates how different biological, psychological, and social factors contribute to chronic pain following total shoulder arthroplasty. By identifying specific patient characteristics, the study aims to develop a precision medicine approach that tailors pain management strategies to individual needs. Participants will be monitored before and after surgery to assess changes in pain and other relevant factors over time. The goal is to create a predictive model that helps identify patients at risk for chronic pain after surgery.
Why it matters
Potential benefit: If successful, this research could lead to more effective pain management strategies for patients undergoing shoulder surgery.
How similar studies have gone: Previous research has shown promise in using precision medicine approaches to improve pain management outcomes in surgical patients.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: George, Steven Z — Duke University
- Study coordinator: George, Steven Z
Related research
Other NIH-funded projects on the same topics.
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Shoulder replacement patients: better pain care through personalized risk profiles
A Duke-led project will look at how biological, psychological, and social factors together predict chronic pain after total shoulder replacement, with the goal of guiding personalized pain management.
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Predicting who develops long-term pain after total shoulder replacement using biological, psychological, and social factors
This project looks for patterns in biology, emotions, and social circumstances that help predict which adults will still have pain one year after total shoulder replacement.
-
Functional electrical stimulation plus shoulder exercises for older adults with rotator cuff pain
In older adults with rotator cuff–related shoulder pain, this study tests whether adding functional electrical stimulation to a shoulder exercise program improves muscle coordination and reduces impingement compared with exercises alone.
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This study tests whether adding respiratory muscle strengthening and diaphragmatic breathing to shoulder rehab can reduce pain and improve sleep in adults with chronic shoulder pain.
-
Night Pain Module for Rotator Cuff-Related Shoulder Pain
Researchers are testing a short set of questions to measure night pain in people with rotator cuff–related shoulder pain to see if it reliably describes how sleep is affected.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.