Understanding how beryllium exposure affects lung health
Predictive Models of Beryllium Sensitization and Chronic Beryllium Disease
This study is looking at how being around beryllium can affect lung health and cause problems like beryllium sensitization and chronic beryllium disease, and it's for people who have been exposed to beryllium to help find out who might be at risk for lung issues in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project ID | NIH-10736862 on NIH RePORTER |
What this research studies
This research investigates the effects of beryllium exposure on lung health, specifically focusing on how it can lead to beryllium sensitization and chronic beryllium disease. The study aims to identify specific gene and protein changes in lung cells that are associated with these conditions. By analyzing samples from individuals exposed to beryllium, the researchers hope to develop models that can predict who is at risk of developing chronic lung issues. This could help in early diagnosis and better management of affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been exposed to beryllium and are experiencing respiratory symptoms or have been diagnosed with beryllium sensitization.
Not a fit: Patients who have not been exposed to beryllium or do not have respiratory issues related to beryllium exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients affected by beryllium-related lung diseases.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for other lung diseases, suggesting that this approach could yield valuable insights into beryllium-related conditions.
Where this research is happening
Denver, United States
- National Jewish Health — Denver, United States (Active)
Researchers
- Principal investigator: Li, Li — National Jewish Health
- Study coordinator: Li, Li
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.