Understanding how beige fat cells change in response to temperature and nutrients
Regulation of beige adipocyte plasticity in inguinal white adipose tissue.
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11046636
This study is looking at how certain fat cells in our bodies can change their activity based on things like temperature and what we eat, with the goal of finding new ways to help people with obesity and metabolic issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11046636 on ClinicalTrials.gov |
What this research studies
This research investigates how beige adipocytes, a type of fat cell, can switch between active and inactive states based on environmental changes, such as temperature and nutrient levels. The study will explore the cellular and molecular mechanisms that regulate this plasticity, focusing on specific gene networks and the role of the extracellular matrix. By examining these processes in both animal models and humans, the research aims to identify potential new treatments for obesity and metabolic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are interested in metabolic health and obesity management.
Not a fit: Patients who are under 21 years old or do not have metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for obesity and related metabolic conditions by targeting the mechanisms that control fat cell behavior.
How similar studies have performed: Previous research has shown promising results in understanding beige adipocyte function and its implications for metabolic health, indicating that this approach has potential for success.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, BIAO — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: WANG, BIAO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.