Understanding how beige fat cells change and adapt in the body
TRANSCRIPTIONAL REGULATION OF BEIGE ADIPOCYTE CELLULAR PLASTICITY
This study is looking at how a special type of fat cell can change its role when exposed to things like cold temperatures, and it's aimed at finding new ways to help people manage their weight and improve their overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11090488 on NIH RePORTER |
What this research studies
This research investigates the unique ability of beige adipocytes, a type of fat cell, to change their identity and function in response to environmental factors like cold exposure. By studying how these cells can switch between different states, the research aims to uncover new mechanisms that could help combat obesity and related metabolic disorders. The approach involves detailed epigenomic analysis to identify key factors that regulate these changes, which could lead to innovative treatments for weight management and metabolic health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are dealing with obesity or related metabolic disorders.
Not a fit: Patients who are not overweight or do not have metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively promote weight loss and improve metabolic health in individuals struggling with obesity.
How similar studies have performed: Previous research has shown promising results in understanding the role of brown and beige adipocytes in metabolism, suggesting that this approach could yield significant insights.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Roh, Hyun Cheol — Indiana University Indianapolis
- Study coordinator: Roh, Hyun Cheol
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.