Understanding how beige fat cells can help manage obesity and diabetes
Regulation of beige adipocyte maintenance and its impact on metabolic outcomes
['FUNDING_R01'] · UNIVERSITY OF ILLINOIS AT CHICAGO · NIH-11047669
This study is looking at how a special type of fat cell that helps burn energy instead of storing it can help fight obesity and diabetes, especially in older people, and aims to find ways to keep these helpful cells around longer for better health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT CHICAGO (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-11047669 on ClinicalTrials.gov |
What this research studies
This research investigates the role of beige adipocytes, a type of fat cell that burns energy instead of storing it, in combating obesity and diabetes. The study aims to understand how these cells can be maintained over time, especially in older individuals, and whether they can improve metabolic health. By using specialized mouse models, researchers will explore pharmacological and genetic methods to induce and sustain these beneficial fat cells. The ultimate goal is to develop new therapeutic strategies that leverage beige adipocytes to enhance metabolic outcomes in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or diabetes, particularly those who are older and may benefit from improved metabolic health.
Not a fit: Patients who do not have issues related to obesity or metabolic diseases may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help manage obesity and diabetes more effectively.
How similar studies have performed: Previous research has shown promising results in using beige adipocytes for metabolic health, suggesting that this approach could be a viable therapeutic strategy.
Where this research is happening
Chicago, UNITED STATES
- UNIVERSITY OF ILLINOIS AT CHICAGO — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JIANG, YUWEI — UNIVERSITY OF ILLINOIS AT CHICAGO
- Study coordinator: JIANG, YUWEI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.