NIH-funded research R01 grant

Understanding how behavioral factors influence opioid and cocaine use

Official title: Opioid and Psychostimulant Taking: Testing the Impact of Behavioral Economic Contexts

Funded at American University · NIH-10893371 · Data updated 2026-11-12

This study looks at why people might struggle with cocaine and opioid use by observing animals to see how money and availability of drugs affect their choices, hoping to find new ways to help reduce drug use.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAmerican University
NIH-funded
Lab location1 site (Washington, UNITED STATES)
Project startSeptember 15, 2022
Project endJuly 31, 2027
Funding year2024
Award (this year)$320,217
NIH project number5R01DA055572-03
Project IDNIH-10893371 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals struggling with opioid or cocaine addiction who may benefit from new treatment strategies.

Less likely to help

Patients who do not use opioids or cocaine, or those with other types of substance use disorders, may not receive direct benefits from this research.

What this research studies

This research investigates the reasons behind substance use disorders, specifically focusing on cocaine and opioid use. By using an animal model, the study examines how different economic contexts affect drug-taking behavior. The researchers will explore how the availability and cost of drugs influence choices between drugs and non-drug rewards. This approach aims to uncover new strategies for reducing drug use by understanding the underlying behavioral economics involved in addiction.

Why it matters

Potential benefit: If successful, this research could lead to more effective interventions for reducing opioid and cocaine use among individuals with substance use disorders.

How similar studies have gone: While the behavioral economic approach to understanding drug use is established, the specific focus on the interplay between opioids and psychostimulants in this context is relatively novel.

Where this research is happening

  • American University
    Washington, United States
    Active

Researchers

  • Principal investigator: Kearns, David N — American University
  • Study coordinator: Kearns, David N

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.