Understanding how bariatric surgery affects blood sugar regulation
The role of diminished CNS hypoglycemia sensing in postbariatric hypoglycemia
This study is looking into why some people who have had weight loss surgery experience low blood sugar without feeling any symptoms, and it aims to understand how the surgery changes brain function and blood sugar regulation to help keep everyone safe and healthy.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10996035 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind postbariatric hypoglycemia (PBH), a condition affecting many patients after weight loss surgery. It focuses on how bariatric surgery alters brain function and the body's ability to sense low blood sugar levels. By studying these changes, the research aims to identify why some patients do not experience symptoms of hypoglycemia, which can lead to serious health risks. The approach includes preclinical studies to explore the brain circuits involved in regulating feeding and glucose levels.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have undergone bariatric surgery and are experiencing symptoms of postbariatric hypoglycemia.
Not a fit: Patients who have not undergone bariatric surgery or do not experience hypoglycemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for patients experiencing dangerous low blood sugar after bariatric surgery.
How similar studies have performed: While there is ongoing research into postbariatric hypoglycemia, this specific investigation into the brain's role in sensing low blood sugar is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Cook, Tyler — University of Colorado Denver
- Study coordinator: Cook, Tyler
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.