Understanding how balance signals are affected by noise in the vestibular system
Vestibular Precision: Physiology and Pathophysiology
This study is looking at how different people’s balance can change because of noise in the part of the inner ear and brain that helps us stay steady, and it’s for anyone interested in understanding balance issues better, especially those with balance disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10875589 on NIH RePORTER |
What this research studies
This research investigates how variability in balance-related responses occurs due to neural noise in the vestibular system, which includes the inner ear and brain pathways responsible for balance. By measuring how well individuals can maintain balance and respond to motion, the study aims to identify the sources of this variability and how it changes when the vestibular system is damaged. The research involves testing normal subjects to quantify their vestibular precision and comparing their responses to predictions made by advanced statistical models. This could lead to a better understanding of balance disorders and how they can be treated.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing balance issues or those with vestibular disorders.
Not a fit: Patients with stable vestibular function and no balance-related symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for balance disorders, enhancing the quality of life for affected patients.
How similar studies have performed: Previous research has shown promising results in understanding vestibular function and its disorders, indicating that this approach has potential for success.
Where this research is happening
Boston, United States
- Massachusetts Eye and Ear Infirmary — Boston, United States (Active)
Researchers
- Principal investigator: Karmali, Faisal — Massachusetts Eye and Ear Infirmary
- Study coordinator: Karmali, Faisal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.