Understanding how bacteria use signaling systems to adapt and survive
Physiological and Developmental Role of Bacterial Ser/Thr Kinases
['FUNDING_OTHER'] · NORTHEASTERN UNIVERSITY · NIH-10894174
This study is looking at how certain bacteria communicate and respond to their surroundings, which could help us understand how they grow and resist antibiotics, ultimately aiming to find better ways to treat infections.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHEASTERN UNIVERSITY (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10894174 on ClinicalTrials.gov |
What this research studies
This research investigates the role of specific bacterial signaling systems, known as Hanks-type serine/threonine kinases and phosphatases, in how bacteria respond to their environment. By studying these systems, the research aims to uncover how they influence bacterial growth, division, and resistance to antibiotics. The approach includes detailed mechanistic studies at both the population and single-cell levels to understand the impact of these signaling pathways on bacterial behavior and their implications for human health. This could lead to new insights into combating antibiotic resistance and improving treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from infections caused by antibiotic-resistant bacteria.
Not a fit: Patients with infections that are easily treatable with existing antibiotics may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for developing anti-infective therapies that are more effective against antibiotic-resistant bacteria.
How similar studies have performed: Previous research has shown promise in understanding bacterial signaling systems, but this specific focus on Hanks-type kinases is relatively novel.
Where this research is happening
BOSTON, UNITED STATES
- NORTHEASTERN UNIVERSITY — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIBBY, ELIZABETH — NORTHEASTERN UNIVERSITY
- Study coordinator: LIBBY, ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.