Understanding how bacteria share genes that help them survive antibiotics
Determinants underlying horizontal gene transfer-mediated pathogen success
This study looks at how bacteria share important traits, like resistance to antibiotics, with each other, which could help us find better ways to tackle antibiotic resistance and keep everyone healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11043058 on NIH RePORTER |
What this research studies
This research investigates how bacteria transfer genetic material to each other, particularly focusing on a process called horizontal gene transfer. By studying how certain bacteria can share traits like antibiotic resistance through physical connections, the research aims to uncover the factors that contribute to the success of these pathogens. The approach includes analyzing various bacterial strains and their environments to understand which combinations thrive and persist. This could lead to better strategies for managing antibiotic resistance and improving public health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by antibiotic-resistant infections or those at risk of such infections.
Not a fit: Patients who do not have any antibiotic-resistant infections or are not at risk may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new methods for combating antibiotic-resistant infections.
How similar studies have performed: Previous research has shown that understanding gene transfer in bacteria can lead to significant advancements in managing antibiotic resistance.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Lopatkin, Allison — University of Rochester
- Study coordinator: Lopatkin, Allison
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.