Understanding how bacteria share genes that help them survive antibiotics
Official title: Determinants underlying horizontal gene transfer-mediated pathogen success
Funded at University of Rochester · NIH-11043058 · Data updated 2026-11-12
This study looks at how bacteria share important traits, like resistance to antibiotics, with each other, which could help us find better ways to tackle antibiotic resistance and keep everyone healthier.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $163,850 |
| NIH project number | 3R35GM150871-02S1 |
| Project ID | NIH-11043058 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by antibiotic-resistant infections or those at risk of such infections.
✕Less likely to help
Patients who do not have any antibiotic-resistant infections or are not at risk may not benefit from this research.
What this research studies
This research investigates how bacteria transfer genetic material to each other, particularly focusing on a process called horizontal gene transfer. By studying how certain bacteria can share traits like antibiotic resistance through physical connections, the research aims to uncover the factors that contribute to the success of these pathogens. The approach includes analyzing various bacterial strains and their environments to understand which combinations thrive and persist. This could lead to better strategies for managing antibiotic resistance and improving public health.
Why it matters
Potential benefit: If successful, this research could lead to new methods for combating antibiotic-resistant infections.
How similar studies have gone: Previous research has shown that understanding gene transfer in bacteria can lead to significant advancements in managing antibiotic resistance.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Lopatkin, Allison — University of Rochester
- Study coordinator: Lopatkin, Allison
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.