Understanding how bacteria share antibiotic resistance genes
Interspecies reservoirs of antibiotic resistance for Neisseria gonorrhoeae
This study is looking into how some bacteria can become resistant to antibiotics, specifically in gonorrhea infections, and it aims to find ways to better track and prevent these tough infections, which could lead to better treatments for patients.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rochester Institute of Technology NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10705474 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind antibiotic resistance in Neisseria gonorrhoeae, a significant public health threat due to rising infection rates and resistant strains. The project focuses on how commensal Neisseria bacteria can share DNA that contributes to resistance, particularly after antibiotic use in patients. By profiling the genetic makeup of these bacteria, the research aims to develop better methods for monitoring and preventing future outbreaks of resistant infections. Patients may benefit from improved treatment strategies and surveillance methods that arise from this work.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with gonorrhea or are at risk of infection.
Not a fit: Patients who are not affected by gonorrhea or those who have already been treated successfully may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment options for antibiotic-resistant gonorrhea.
How similar studies have performed: Previous research has shown that understanding bacterial genetics can lead to significant advancements in managing antibiotic resistance, indicating that this approach has potential for success.
Where this research is happening
Rochester, United States
- Rochester Institute of Technology — Rochester, United States (Active)
Researchers
- Principal investigator: Wadsworth, Crista Burke — Rochester Institute of Technology
- Study coordinator: Wadsworth, Crista Burke
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.