Understanding how bacteria interact during gonorrhea infections
Polymicrobial Context of Neisseria gonorrhoeae Infection and Mucosal Immune Response
['FUNDING_OTHER'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-11059856
This study is looking at how the bacteria that cause gonorrhea interact with your body's immune system in a special 3D model of the cervix and vagina, which could help us find better treatments for infections like this in the future.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11059856 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between the bacteria involved in gonorrhea infections and the body's immune response. By creating a 3D model of the cervicovaginal environment, researchers aim to observe how these bacteria and the host's microbiome influence each other during infection. The study employs advanced techniques such as RNA sequencing and immune profiling to gather comprehensive data on these interactions. Patients may benefit from insights that could lead to improved treatments for sexually transmitted infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are experiencing or are at risk for gonorrhea or chlamydia infections.
Not a fit: Patients who do not have sexually transmitted infections or those who are not sexually active may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for gonorrhea and related infections.
How similar studies have performed: Previous research has shown promise in understanding bacterial interactions in similar contexts, suggesting that this approach could yield valuable insights.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CRISS, ALISON K — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: CRISS, ALISON K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.