Understanding How Bacteria in Our Bodies Respond to Their Environment
High-Resolution Mapping of Bacterial Transcriptional Responses in Human-Associated Microbiota
['FUNDING_R01'] · CORNELL UNIVERSITY · NIH-11089331
This project aims to better understand how the bacteria living inside us react and adapt to their surroundings, which is key to our overall health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-11089331 on ClinicalTrials.gov |
What this research studies
Our bodies are home to many bacteria, collectively known as the microbiome, and their actions greatly influence our health. While we can identify which bacteria are present, it's harder to know exactly what they are doing at any given moment. This research is developing new, highly detailed tools to map out how these bacteria turn on or off different functions in response to what's happening around them. By looking closely at these 'transcriptional responses,' we can learn how bacteria survive, adapt, and sometimes cause problems, especially when facing things like antibiotics or changes in their environment.
Who could benefit from this research
Good fit: This foundational laboratory research does not directly involve patient participation, but it focuses on understanding the human microbiome.
Not a fit: Patients seeking immediate direct treatment or intervention would not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of how our microbiome affects health and disease, potentially guiding new ways to treat infections or improve gut health.
How similar studies have performed: While traditional methods for studying bacterial responses exist, this project aims to develop more sensitive and comprehensive tools to overcome their limitations.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BRITO, ILANA LAUREN — CORNELL UNIVERSITY
- Study coordinator: BRITO, ILANA LAUREN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.