Understanding how bacteria grow and adapt to their environment
Local and global regulation of bacterial growth
This study looks at how a specific type of bacteria, called Caulobacter crescentus, grows and changes when faced with challenges like antibiotics, which could help us find better ways to treat infections that don't respond to current medicines.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11089199 on NIH RePORTER |
What this research studies
This research investigates how bacteria, particularly the alphaproteobacterium Caulobacter crescentus, reproduce and adapt to environmental changes, including antibiotic stress. By examining the mechanisms of cell division and the role of the cell envelope, the research aims to uncover how bacteria maintain their integrity and survive. The study employs various techniques such as genetics, biochemistry, and advanced imaging to explore these processes in detail. Patients may benefit from insights gained that could lead to improved treatments for antibiotic-resistant infections.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals suffering from infections caused by antibiotic-resistant bacteria.
Not a fit: Patients with infections that are not caused by bacterial pathogens or those who do not have antibiotic resistance issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for combating antibiotic-resistant bacterial infections.
How similar studies have performed: Other research has shown success in understanding bacterial growth and antibiotic resistance, making this approach both relevant and promising.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Goley, Erin D — Johns Hopkins University
- Study coordinator: Goley, Erin D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.